TB-500 (10mg)
Price range: $55.00 through $345.00
Third-party COA: HPLC purity 99.85% · ILS Laboratories · Lot 2026-01
TB-500 is supplied as full-length thymosin beta-4 (Tβ4), a 43-amino-acid peptide, per our supplier; the COA confirms identity by HPLC retention time. Supplied in lyophilized powder form for laboratory research.
TB-500 is synthetic thymosin beta-4 (Tβ4), a 43-residue, N-terminally acetylated protein known in biochemistry for binding monomeric actin. M-Rogue Research supplies TB-500 as a lyophilized powder in a 10mg vial, shipped from our California warehouse.
Per our supplier, the TB-500 supplied by M-Rogue Research is the full-length, 43-residue thymosin beta-4 (Tβ4) sequence, not the short 17–23 fragment (Ac-LKKTETQ) that the TB-500 name sometimes refers to elsewhere in the research-peptide market. The ILS Laboratories COA for our lot confirms identity (reported as “TB-4”) by HPLC retention-time comparison. In the laboratory, Tβ4 is used in cell-free actin-binding assays, in vitro cell-culture studies and analytical method development.
Chemical Specifications
| Property | Thymosin β4 (full length) |
|---|---|
| CAS number | 77591-33-4 |
| IUPAC name | Not listed (long peptide) |
| Molecular formula | C212H350N56O78S |
| Molecular weight | 4963 g/mol |
| Sequence | Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES-OH |
Third-Party Testing & Verification
The current lot of TB-500 10mg (lot 2026-01) was analyzed by ILS Laboratories in San Diego, California. The certificate lists M Rogue Research as the client (“Tested for: M Rogue Research”).
Certificate COA-2026-S5VB1M (analysis date 08/25/2026) reports an HPLC peptide purity of 99.85% against a specification of ≥95.0%, a net peptide content of 10.62 mg, identity confirmed by HPLC retention-time comparison with a reference standard, and a fentanyl immunoassay screen (50 ng/mL cutoff) reported as not detected. Purity is calculated by reversed-phase HPLC area normalization at 214 nm, as the percentage of the target peptide relative to all peptide-related peaks. The COA lists the identity analyte as “TB-4”.
This COA covers lot 2026-01 only. It reports HPLC data and does not include mass-spectrometry data. View the TB-500 10mg COA
Storage & Reconstitution Guidelines
TB-500 10mg is supplied as a lyophilized (freeze-dried) powder in a sealed vial. In this form the peptide is considerably more stable than in solution, but it is still sensitive to moisture, heat and light. On receipt, store the unopened vial at -20°C, protected from light, in a dry container. Short periods at room temperature during transit are normal for lyophilized material.
Before opening, allow the vial to reach room temperature (typically 15–30 minutes) so that atmospheric moisture does not condense on the cold powder. Reconstitute with a solvent appropriate to your assay, such as sterile water or a suitable buffer; some sequences dissolve more readily in a small volume of dilute acetic acid or DMSO before dilution. Add solvent slowly down the vial wall and swirl gently rather than shaking or vortexing.
Once in solution, divide the material into single-use aliquots to avoid repeated freeze-thaw cycles. Store aliquots at -20°C (or -80°C for longer periods) and keep solutions in use at 2–8°C for short periods only. Record the lot number, solvent, concentration and date on every aliquot. For a full walkthrough, see our guide on lyophilized peptide handling, reconstitution and storage.
Compliance Disclaimer
All compounds are intended strictly for laboratory and scientific research purposes only. Not for human or animal consumption. For research purposes only. Not for human consumption. 21+.
Documentation & Further Reading
| Size |
Single Vial ,Half Kit (5 Vials) ,Whole Kit (10 Vials) |
|---|
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